α-2 Macroglobulin gene and Alzheimer disease

V Rudrasingham, WD Vrieze, JC Lambert… - Nature …, 1999 - nature.com
V Rudrasingham, WD Vrieze, JC Lambert, S Chakraverty, P Kehoe, R Crook, P Amouyel
Nature genetics, 1999nature.com
(Table 2), as well as the summary statistics (Table 1). We did not observe an association
between AD and possession of at least one copy of the deletion (P= 0.7) in the sample
overall. We also failed to detect an allelic association (P= 0.4), although the combined
sample showed the expected association between AD and APOE* E4 (P< 10–10, OR= 4.6,
95% confidence interval (CI)= 3.9− 5.5).
(Table 2), as well as the summary statistics (Table 1). We did not observe an association between AD and possession of at least one copy of the deletion (P= 0.7) in the sample overall. We also failed to detect an allelic association (P= 0.4), although the combined sample showed the expected association between AD and APOE* E4 (P< 10–10, OR= 4.6, 95% confidence interval (CI)= 3.9− 5.5).
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