Stress-induced glucocorticoid response modulates mononuclear cell trafficking during an experimental influenza viral infection
G Hermann, FM Beck, JF Sheridan - Journal of Neuroimmunology, 1995 - Elsevier
The migration, distribution, and localization of lymphoid cells throughout the body is critical
to the efficiency and development of the immune response. This study examined the role of
endogenous glucocorticoids in mononuclear cell (MNC) trafficking during the development
of an immune response to infection by influenza A/PR8 virus. Accumulation of MNC in the
draining lymph nodes and at the site of virus replication (lungs) was studied in infected mice,
and infected mice subjected to a Stressor (physical restraint). The glucocorticoid antagonist …
to the efficiency and development of the immune response. This study examined the role of
endogenous glucocorticoids in mononuclear cell (MNC) trafficking during the development
of an immune response to infection by influenza A/PR8 virus. Accumulation of MNC in the
draining lymph nodes and at the site of virus replication (lungs) was studied in infected mice,
and infected mice subjected to a Stressor (physical restraint). The glucocorticoid antagonist …
