Lymphocyte migration into tissue: the paradigm derived from CD4 subsets
LM Bradley, SR Watson - Current opinion in immunology, 1996 - Elsevier
LM Bradley, SR Watson
Current opinion in immunology, 1996•ElsevierThe appropriate recirculation and migration of naive, effector and memory T cells into
inflamed tissue are precisely controlled by adhesive interactions with vascular endothelium.
Analyses of CD4 lymphocytes have indicated that naive and antigen-experienced cells
exhibit distinctive patterns of homing and recirculation, and that subsets of cells
preferentially localize in different anatomical locations as a consequence of previous
antigen exposure and differences in adhesion receptor usage.
inflamed tissue are precisely controlled by adhesive interactions with vascular endothelium.
Analyses of CD4 lymphocytes have indicated that naive and antigen-experienced cells
exhibit distinctive patterns of homing and recirculation, and that subsets of cells
preferentially localize in different anatomical locations as a consequence of previous
antigen exposure and differences in adhesion receptor usage.
The appropriate recirculation and migration of naive, effector and memory T cells into inflamed tissue are precisely controlled by adhesive interactions with vascular endothelium. Analyses of CD4 lymphocytes have indicated that naive and antigen-experienced cells exhibit distinctive patterns of homing and recirculation, and that subsets of cells preferentially localize in different anatomical locations as a consequence of previous antigen exposure and differences in adhesion receptor usage.
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