[PDF][PDF] NADPH oxidase contributes directly to oxidative stress and apoptosis in nerve growth factor-deprived sympathetic neurons

SP Tammariello, MT Quinn… - The Journal of …, 2000 - Soc Neuroscience
The Journal of Neuroscience, 2000Soc Neuroscience
t NADPH Oxidase Contributes Directly to Oxidative Stress and Apoptosis in Nerve Growth
Factor-Deprived Sympathetic Neurons Page 1 NADPH Oxidase Contributes Directly to Oxidative
Stress and Apoptosis in Nerve Growth Factor-Deprived Sympathetic Neurons Steven P.
Tammariello,1 Mark T. Quinn,2 and Steven Estus1 1Department of Physiology, Sanders-Brown
Center on Aging, University of Kentucky, Lexington, Kentucky 40536, 2Department of
Veterinary Molecular Biology, Montana State University, Bozeman, Montana 59717 Reactive …
NAPDH oxidase genetic deficiency inhibit apoptosis in a classic model of PCD, ie, NGF-deprived sympathetic neurons. Overall, these results indicate that NADPH oxidase is unexpectedly present in neurons and can contribute to neuronal apoptosis.
Soc Neuroscience