[HTML][HTML] Autoreactive CD8 T cells in organ-specific autoimmunity: emerging targets for therapeutic intervention
Immunity, 2002•cell.com
The importance of CD8 T cells in the pathogenesis of organ-specific autoimmune diseases
has not previously been well recognized. Recent evidence, however, indicates that
autoreactive CD8 T cells can contribute substantially to tissue damage in both murine and
human autoimmune disorders. As such, these T cells now become an attractive target for
therapeutic intervention.
has not previously been well recognized. Recent evidence, however, indicates that
autoreactive CD8 T cells can contribute substantially to tissue damage in both murine and
human autoimmune disorders. As such, these T cells now become an attractive target for
therapeutic intervention.
Abstract
The importance of CD8 T cells in the pathogenesis of organ-specific autoimmune diseases has not previously been well recognized. Recent evidence, however, indicates that autoreactive CD8 T cells can contribute substantially to tissue damage in both murine and human autoimmune disorders. As such, these T cells now become an attractive target for therapeutic intervention.
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