New model for the regulation of energy balance and adiposity by the central nervous system

KJ Kaiyala, SC Woods, MW Schwartz - The American journal of clinical …, 1995 - Elsevier
We describe a new model for adiposity regulation in which two distinct classes of peripheral
afferent signals modulate neuronal pathways in the brain that control meal initiation, meal
termination, and the autonomic outflow influencing the fate of ingested energy. These brain
pathways, termed central-effector pathways for the control of energy balance, respond to 1)
short-term, situational-, and meal-related signals that are crucial to the size and timing of
individual meals, but that are not components of the system serving to regulate adipose …