[HTML][HTML] An imprinted PEG1/MEST antisense expressed predominantly in human testis and in mature spermatozoa
T Li, TH Vu, KO Lee, Y Yang, CV Nguyen… - Journal of Biological …, 2002 - ASBMB
PEG1 (or MEST) is an imprinted gene located on human chromosome 7q32 that is
expressed predominantly from the paternal allele. In the mouse, Peg1/Mest is associated
with embryonic growth and maternal behavior. Human PEG1 is transcribed from two
promoters; the transcript from promoter P1 is derived from both parental alleles, and the
transcript from P2 is exclusively from the paternal allele. We characterized the P1 and P2
transcripts in various normal and neoplastic tissues. In the normal tissues, PEG1was …
expressed predominantly from the paternal allele. In the mouse, Peg1/Mest is associated
with embryonic growth and maternal behavior. Human PEG1 is transcribed from two
promoters; the transcript from promoter P1 is derived from both parental alleles, and the
transcript from P2 is exclusively from the paternal allele. We characterized the P1 and P2
transcripts in various normal and neoplastic tissues. In the normal tissues, PEG1was …
