Evidence for basolateral P2Y6 receptors along the rat proximal tubule: functional and molecular characterization

MA Bailey, M Imbert-Teboul, C Turner… - Journal of the …, 2001 - journals.lww.com
In this study, the distribution of P2Y 6 receptor mRNA in rat nephron segments was
investigated and a functional approach was used to analyze basolateral protein expression.
Reverse transcription-PCR studies revealed more intense expression of P2Y 6 receptor
mRNA in the proximal tubule and the thick ascending limb of Henle's loop, less intense
expression in the thin descending limb and the cortical and outer medullary collecting ducts,
and no detectable expression in either the thin ascending limb or the inner medullary …