Trousseau's syndrome. Devastating coagulopathy in the absence of heparin

WR Bell, NF Starksen, S Tong, JK Porterfield - The American journal of …, 1985 - Elsevier
Two patients with Trousseau's syndrome experienced frequently recurring concomitant
arterial and venous thrombotic events that resulted in sequential amputation and loss of the
lower extremities. Serial examination of the blood in the patients demonstrated that these
devastating thrombotic events were preceded by severe disseminated intravascular
coagulopathy that occurred within an Interval of a few hours. Warfarin therapy was without
effect in preventing the occurrence of these events. Both patients demonstrated the absolute …