[HTML][HTML] Molecular cloning of a novel human CC chemokine liver and activation-regulated chemokine (LARC) expressed in liver: chemotactic activity for lymphocytes …

K Hieshima, T Imai, G Opdenakker… - Journal of Biological …, 1997 - ASBMB
Partial overlapping cDNA sequences likely to encode a novel human CC chemokine were
identified from the GenBank Expressed Sequence Tag data base. Using these sequences,
we isolated full-length cDNA encoding a protein of 96 amino acid residues with 20-28%
identity to other CC chemokines. By Northern blot, this chemokine was mainly expressed in
liver among various tissues and strongly induced in several human cell lines by phorbol
myristate acetate. We thus designated this chemokine as LARC from iver and ctivation …