Sequential MRI in a case of Creutzfeldt-Jakob disease
G Tribl, G Strasser, J Zeitlhofer, S Asenbaum, C Jarius… - Neuroradiology, 2002 - Springer
G Tribl, G Strasser, J Zeitlhofer, S Asenbaum, C Jarius, P Wessely, D Prayer
Neuroradiology, 2002•SpringerA 48-year-old man suddenly developed clinically and electroencephalographically
nonspecific dementia. On MRI sequences, only diffusion-weighted images (DWI) of the
cortex were unequivocally pathological. Obvious atrophy and basal ganglia signal changes
appeared only 9 months after the onset. Brain biopsy confirmed Creutzfeldt-Jakob disease
(CJD). In rapidly progressive dementia, we recommend DWI for early diagnosis of CJD.
nonspecific dementia. On MRI sequences, only diffusion-weighted images (DWI) of the
cortex were unequivocally pathological. Obvious atrophy and basal ganglia signal changes
appeared only 9 months after the onset. Brain biopsy confirmed Creutzfeldt-Jakob disease
(CJD). In rapidly progressive dementia, we recommend DWI for early diagnosis of CJD.
Abstract
A 48-year-old man suddenly developed clinically and electroencephalographically nonspecific dementia. On MRI sequences, only diffusion-weighted images (DWI) of the cortex were unequivocally pathological. Obvious atrophy and basal ganglia signal changes appeared only 9 months after the onset. Brain biopsy confirmed Creutzfeldt-Jakob disease (CJD). In rapidly progressive dementia, we recommend DWI for early diagnosis of CJD.
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