[HTML][HTML] Comparison of Cak1p-like cyclin-dependent kinase-activating kinases
V Tsakraklides, MJ Solomon - Journal of Biological Chemistry, 2002 - ASBMB
Cyclin-dependent kinases (cdks) coordinate progression through the eukaryotic cell cycle
and require phosphorylation by a cdk-activating kinase (CAK) for full activity. In most
eukaryotes Cdk7 is the catalytic subunit of a heterotrimeric CAK (Cdk7-cyclin H-Mat1) that is
also involved in transcription as part of the transcription factor IIH complex. The
Saccharomyces cerevisiae CAK, Cak1p, is a monomeric protein kinase with an atypical
sequence and unusual biochemical properties compared with trimeric CAKs and other …
and require phosphorylation by a cdk-activating kinase (CAK) for full activity. In most
eukaryotes Cdk7 is the catalytic subunit of a heterotrimeric CAK (Cdk7-cyclin H-Mat1) that is
also involved in transcription as part of the transcription factor IIH complex. The
Saccharomyces cerevisiae CAK, Cak1p, is a monomeric protein kinase with an atypical
sequence and unusual biochemical properties compared with trimeric CAKs and other …
