[HTML][HTML] Structural and functional genomics of the CPT1B gene for muscle-type carnitine palmitoyltransferase I in mammals
FR van der Leij, KB Cox, VN Jackson… - Journal of Biological …, 2002 - ASBMB
Muscle-type carnitine palmitoyltransferase I (M-CPT I) is a key enzyme in the control of β-
oxidation of long-chain fatty acids in the heart and skeletal muscle. Because knowledge of
the mammalian genes encoding M-CPT I may aid in studies of disturbed energy metabolism,
we obtained new genomic and cDNA data for M-CPT I for the human, mouse, rat, and
sheep. The introns of these compact genes are 80%(mouse versus rat) and 60%(mouse
versus human) identical. Sheep and goat, but not cow, pig, rodent, or human promoter …
oxidation of long-chain fatty acids in the heart and skeletal muscle. Because knowledge of
the mammalian genes encoding M-CPT I may aid in studies of disturbed energy metabolism,
we obtained new genomic and cDNA data for M-CPT I for the human, mouse, rat, and
sheep. The introns of these compact genes are 80%(mouse versus rat) and 60%(mouse
versus human) identical. Sheep and goat, but not cow, pig, rodent, or human promoter …
