p63 expression in breast cancer: a highly sensitive and specific marker of metaplastic carcinoma
MM Koker, CG Kleer - The American journal of surgical pathology, 2004 - journals.lww.com
Abstract p63, a member of the p53 gene family, is involved in cellular differentiation and is
expressed in the nuclei of myoepithelial cells of normal breast ducts and lobules. Although
p63 has been reported in metaplastic carcinomas of the breast, its expression pattern in
breast carcinomas and sarcomas has not been fully characterized, and its potential
diagnostic utility has not been defined. In this study, we determined p63 expression in a
large number of breast carcinomas, including metaplastic carcinomas, and in Phyllodes …
expressed in the nuclei of myoepithelial cells of normal breast ducts and lobules. Although
p63 has been reported in metaplastic carcinomas of the breast, its expression pattern in
breast carcinomas and sarcomas has not been fully characterized, and its potential
diagnostic utility has not been defined. In this study, we determined p63 expression in a
large number of breast carcinomas, including metaplastic carcinomas, and in Phyllodes …