Estrogen-receptor status and outcomes of modern chemotherapy for patients with node-positive breast cancer
DA Berry, C Cirrincione, IC Henderson, ML Citron… - Jama, 2006 - jamanetwork.com
ContextBreast cancer estrogen-receptor (ER) status is useful in predicting benefit from
endocrine therapy. It may also help predict which patients benefit from advances in adjuvant
chemotherapy. ObjectiveTo compare differences in benefits from adjuvant chemotherapy
achieved by patients with ER-negative vs ER-positive tumors. Design, Setting, and
PatientsTrial data from the Cancer and Leukemia Group B and US Breast Cancer Intergroup
analyzed; patient outcomes by ER status compared using hazards over time and …
endocrine therapy. It may also help predict which patients benefit from advances in adjuvant
chemotherapy. ObjectiveTo compare differences in benefits from adjuvant chemotherapy
achieved by patients with ER-negative vs ER-positive tumors. Design, Setting, and
PatientsTrial data from the Cancer and Leukemia Group B and US Breast Cancer Intergroup
analyzed; patient outcomes by ER status compared using hazards over time and …