Diagnostic markers of infection in neonates

PC Ng - Archives of Disease in Childhood-Fetal and Neonatal …, 2004 - fn.bmj.com
PC Ng
Archives of Disease in Childhood-Fetal and Neonatal Edition, 2004fn.bmj.com
Diagnostic markers of infection are useful indicators of neonatal sepsis. Serial
measurements of infection markers can improve diagnostic sensitivity, and the use of
multiple markers can enhance diagnostic accuracy. Current evidence suggests that
promising markers may be useful for early termination of antimicrobial treatment, but none of
the current diagnostic tests are sensitive and specific enough to influence the clinical
decision for withholding antibiotic treatment at the onset of suspected infection.
Diagnostic markers of infection are useful indicators of neonatal sepsis. Serial measurements of infection markers can improve diagnostic sensitivity, and the use of multiple markers can enhance diagnostic accuracy. Current evidence suggests that promising markers may be useful for early termination of antimicrobial treatment, but none of the current diagnostic tests are sensitive and specific enough to influence the clinical decision for withholding antibiotic treatment at the onset of suspected infection.
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