Secondary syphilis in persons infected with and not infected with HIV-1: a comparative immunohistologic study
RL McBroom, AR Styles, MJ Chiu… - The American journal …, 1999 - journals.lww.com
To better understand the cutaneous immune response to Treponema pallidum, we
performed an immunohistologic study of skin biopsies from a total of 11 patients with
secondary syphilis; biopsies from five persons infected with HIV-1 were included in the
analysis to assess at the tissue level the impact of concomitant HIV-1 infection on disease
expression. In all of the biopsies, staining for HLA-DR, a marker for cellular activation, was
observed among infiltrating leukocytes, dermal vascular endothelial cells, and keratinocytes …
performed an immunohistologic study of skin biopsies from a total of 11 patients with
secondary syphilis; biopsies from five persons infected with HIV-1 were included in the
analysis to assess at the tissue level the impact of concomitant HIV-1 infection on disease
expression. In all of the biopsies, staining for HLA-DR, a marker for cellular activation, was
observed among infiltrating leukocytes, dermal vascular endothelial cells, and keratinocytes …