BACKGROUND/AIMS: The molecular basis of hepatic dysfunction in thyrotoxicosis is not
fully understood. Here, we investigated the effect of altered thyroidal status on death
receptor pathways including p75 neurotrophin receptor (p75NTR), a member of tumor
necrosis factor (TNF) receptor superfamily, in rat liver. METHODS: Hyperthyroidism was
induced in Sprague–Dawley rats by daily injections of triiodothyronine in a dose of 12.5
μg/100g body weight for 10 days. RESULTS: Terminal deoxynucleotide-transferase …