[PDF][PDF] Interleukin-10 drives human monocytes to CD16 positive macrophages

JC Calzada-Wack, M Frankenberger… - Journal of …, 1996 - researchgate.net
The receptors for the Pc portion of IgG on monocytes and macrophages form a cen-tral
element in the inflamma-tory response, since binding of antigen via IgG will lead to cell
activation, phagocytosis, and destruction of foreign material. Cells of the monocyte lineage
express Fc receptor types I, II, and III (CD64, CD32, and CD16, respectively). Among these,
the phagocyte restricted CD64 and the more broadly distributed CD32 are found on blood
monocytes and on the various tissue macrophages. The CD16 molecule is, however …