Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract

X Shao, S Somlo, P Igarashi - Journal of the American Society of …, 2002 - journals.lww.com
Ksp-cadherin is a unique, tissue-specific member of the cadherin family of cell adhesion
molecules that is expressed in tubular epithelial cells in the kidney and developing
genitourinary (GU) tract. It has recently been shown that a 1341-bp fragment of the 5′
flanking region containing the Ksp-cadherin gene promoter can recapitulate the complete
expression pattern of the gene in the developing kidney and GU tract. Similar to the
endogenous Ksp-cadherin gene, transgenes containing 1341 bp of the 5′ flanking region …