Macrophages in rheumatoid arthritis
N Maruotti, FP Cantatore, E Crivellato… - Histology and …, 2007 - digitum.um.es
Histology and histopathology, 2007•digitum.um.es
In rheumatoid arthritis (RA) tissue macrophages release growth factors, matrix
metalloproteinases, cytokines, and chemokines. While in normal joints there is a balance
between proinflammatory and anti-inflammatory cytokines, an imbalance between these
inducers and inhibitors of inflammation occurs in RA, where macrophages are responsible
for inducing inflammation, matrix destruction and angiogenesis.
metalloproteinases, cytokines, and chemokines. While in normal joints there is a balance
between proinflammatory and anti-inflammatory cytokines, an imbalance between these
inducers and inhibitors of inflammation occurs in RA, where macrophages are responsible
for inducing inflammation, matrix destruction and angiogenesis.
In rheumatoid arthritis (RA) tissue macrophages release growth factors, matrix metalloproteinases, cytokines, and chemokines. While in normal joints there is a balance between proinflammatory and anti-inflammatory cytokines, an imbalance between these inducers and inhibitors of inflammation occurs in RA, where macrophages are responsible for inducing inflammation, matrix destruction and angiogenesis.
digitum.um.es