Brown fat as a therapy for obesity and diabetes
AM Cypess, CR Kahn - Current Opinion in Endocrinology …, 2010 - journals.lww.com
AM Cypess, CR Kahn
Current Opinion in Endocrinology, Diabetes and Obesity, 2010•journals.lww.comAdult humans have functional BAT, a new target for antiobesity and antidiabetes therapies
focusing on increasing energy expenditure. Future studies will refine the methodologies
used to measure BAT mass and activity, expand our knowledge of critical-control points in
BAT regulation, and focus on testing pharmacological agents that increase BAT
thermogenesis and help achieve long-lasting weight loss and an improved metabolic profile.
focusing on increasing energy expenditure. Future studies will refine the methodologies
used to measure BAT mass and activity, expand our knowledge of critical-control points in
BAT regulation, and focus on testing pharmacological agents that increase BAT
thermogenesis and help achieve long-lasting weight loss and an improved metabolic profile.
Summary
Adult humans have functional BAT, a new target for antiobesity and antidiabetes therapies focusing on increasing energy expenditure. Future studies will refine the methodologies used to measure BAT mass and activity, expand our knowledge of critical-control points in BAT regulation, and focus on testing pharmacological agents that increase BAT thermogenesis and help achieve long-lasting weight loss and an improved metabolic profile.
Lippincott Williams & Wilkins