[PDF][PDF] Inflammation joins the “niche”
Bone marrow-derived cells have an important role in tumor metastasis and have been
reported to" prime" distant tissues for tumor engraftment, although the mechanisms for their
recruitment have remained unclear. A new study by Hiratsuka et al. describes an
inflammatory signaling pathway that mediates the chemoattraction of myeloid and tumor
cells to organ-specific metastatic sites.
reported to" prime" distant tissues for tumor engraftment, although the mechanisms for their
recruitment have remained unclear. A new study by Hiratsuka et al. describes an
inflammatory signaling pathway that mediates the chemoattraction of myeloid and tumor
cells to organ-specific metastatic sites.
Bone marrow-derived cells have an important role in tumor metastasis and have been reported to "prime" distant tissues for tumor engraftment, although the mechanisms for their recruitment have remained unclear. A new study by Hiratsuka et al. describes an inflammatory signaling pathway that mediates the chemoattraction of myeloid and tumor cells to organ-specific metastatic sites.
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