Observations on thrombolastographic patterns and coagulation changes in malnutrition (Marasmus and Kwashiorkor).

K Jain, SD Singh, DP Mukerjee - 1979 - cabidigitallibrary.org
K Jain, SD Singh, DP Mukerjee
1979cabidigitallibrary.org
In 50 patients with marasmus and kwashiorkor the thrombolastograph was used to study the
kinetics of clot formation and the elasticity of the clot finally formed. Thrombocytopenia was
found in 6%, prolonged bleeding time in 4%, poor clot retraction in 82% and poor factor V
activity in 26% of the patients. Different types of thrombolastographic patterns were found: a
normal pattern in 24%, a hypercoagulable pattern in 10% and a hypocoagulable pattern in
66% of the patients. The thrombolastogram was useful in screening children with …
Abstract
In 50 patients with marasmus and kwashiorkor the thrombolastograph was used to study the kinetics of clot formation and the elasticity of the clot finally formed. Thrombocytopenia was found in 6%, prolonged bleeding time in 4%, poor clot retraction in 82% and poor factor V activity in 26% of the patients. Different types of thrombolastographic patterns were found: a normal pattern in 24%, a hypercoagulable pattern in 10% and a hypocoagulable pattern in 66% of the patients. The thrombolastogram was useful in screening children with hypercoagulable patterns who were more susceptible to disseminated intravascular coagulation when under "stress".
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