Natural killer cells in peripheral blood and lung tissue are associated with chronic rejection after lung transplantation
JE Fildes, N Yonan, K Tunstall, AH Walker… - The Journal of heart and …, 2008 - Elsevier
BACKGROUND: Natural killer (NK) cells have the capacity to recognize and respond to
alloantigen, yet their role in lung transplant rejection is not well defined. The aim of this study
was to correlate NK cell numbers and immunophenotype in peripheral blood and tissue with
graft function after lung transplantation. METHODS: NK cell subsets were
immunophenotyped in peripheral blood (n= 41). Lung tissue was stained for NK cells via
CD16 and morphologic assessment (n= 30). RESULTS: Peripheral blood NK cells were …
alloantigen, yet their role in lung transplant rejection is not well defined. The aim of this study
was to correlate NK cell numbers and immunophenotype in peripheral blood and tissue with
graft function after lung transplantation. METHODS: NK cell subsets were
immunophenotyped in peripheral blood (n= 41). Lung tissue was stained for NK cells via
CD16 and morphologic assessment (n= 30). RESULTS: Peripheral blood NK cells were …