In endothermic animals, brown adipose tissue (BAT) is activated to produce heat for
defending body temperature in response to cold. BAT's ability to expend energy has made it
a potential target for novel therapies to ameliorate obesity and associated metabolic
disorders in humans. Though this tissue has been well studied in small animals, BAT's
thermogenic capacity in humans remains largely unknown due to the difficulties of
measuring its volume, activity, and distribution. Identifying and quantifying active human BAT …