Prevalence of depression and anxiety in multiple sclerosis: a systematic review and meta-analysis

RE Boeschoten, AMJ Braamse, ATF Beekman… - Journal of the …, 2017 - Elsevier
Objective Prevalence rates of depression and anxiety in patients with Multiple Sclerosis
(MS) vary widely across studies. Aim of this systematic review and meta-analysis was to a)
estimate the prevalence of depression and anxiety in MS, and specifically b) explore
sources of heterogeneity (assessment method, prevalence period, study quality, recruitment
resource, region) by extensive analyses. Methods A computerized search in PubMed,
EMBASE, and PsycINFO for studies on depression and anxiety in MS was performed up to …