[HTML][HTML] Platelet function in sepsis

A Yaguchi, FLM Lobo, JL Vincent, O Pradier - Journal of thrombosis and …, 2004 - Elsevier
Background: Coagulation abnormalities and thrombocytopenia are common in severe
sepsis, but sepsis‐related alterations in platelet function are ill‐defined. Objectives: The
purpose of this study was to elucidate the effect of sepsis on platelet aggregation,
adhesiveness, and growth factor release. Patients and methods: Agonist‐induced platelet
aggregation was measured in platelet‐rich plasma separated from blood samples collected
from 47 critically ill patients with sepsis of recent onset. Expression of platelet adhesion …