Complex developmental programs require orchestration of intrinsic and extrinsic signals to
control cell proliferation, differentiation, and survival. Master regulatory transcription factors
are vital components of the machinery that transduce these stimuli into cellular responses.
This is exemplified by the GATA family of transcription factors that establish cell type-specific
genetic networks and control the development and homeostasis of systems including blood,
vascular, adipose, and cardiac. Dysregulated GATA factor activity/expression underlies …