[HTML][HTML] Obesity is associated with senescence of mesenchymal stromal cells derived from bone marrow, subcutaneous and visceral fat of young mice
N Alessio, MB Acar, IH Demirsoy, T Squillaro… - Aging (albany …, 2020 - ncbi.nlm.nih.gov
N Alessio, MB Acar, IH Demirsoy, T Squillaro, D Siniscalco, G Di Bernardo, G Peluso…
Aging (albany NY), 2020•ncbi.nlm.nih.govWhite adipose tissue (WAT) is distributed in several depots with distinct metabolic and
inflammatory functions. In our body there are subcutaneous (sWAT), visceral (vWAT) and
bone marrow (bWAT) fat depots. Obesity affects the size, function and inflammatory state of
WATs. In particular, obesity may affect the activity of mesenchymal stromal cells (MSCs)
present in WAT. MSCs are a heterogeneous population containing stromal cells, progenitor
cells, fibroblasts and stem cells that are able to differentiate among adipocytes …
inflammatory functions. In our body there are subcutaneous (sWAT), visceral (vWAT) and
bone marrow (bWAT) fat depots. Obesity affects the size, function and inflammatory state of
WATs. In particular, obesity may affect the activity of mesenchymal stromal cells (MSCs)
present in WAT. MSCs are a heterogeneous population containing stromal cells, progenitor
cells, fibroblasts and stem cells that are able to differentiate among adipocytes …
Abstract
White adipose tissue (WAT) is distributed in several depots with distinct metabolic and inflammatory functions. In our body there are subcutaneous (sWAT), visceral (vWAT) and bone marrow (bWAT) fat depots. Obesity affects the size, function and inflammatory state of WATs. In particular, obesity may affect the activity of mesenchymal stromal cells (MSCs) present in WAT. MSCs are a heterogeneous population containing stromal cells, progenitor cells, fibroblasts and stem cells that are able to differentiate among adipocytes, chondrocytes, osteocytes and other mesodermal derivatives.
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