Ghrelin is a peptide hormone that has been implicated in the regulation of food intake and
energy homeostasis. Ghrelin is predominantly produced in the stomach, but is also
expressed in many other tissues where its functions are not well characterized. In the rodent
and human pancreas, ghrelin levels peak at late gestation and gradually decline postnatally.
Several studies have suggested that ghrelin regulates beta cell function during embryonic
development and in the adult. In addition, in a number of mouse models, ghrelin cells …