Enriched blood IgG sialylation attenuates IgG-mediated and IgG-controlled-IgE-mediated allergic reactions
J Petry, J Rahmöller, L Dühring… - Journal of Allergy and …, 2021 - jacionline.org
Hence, analyzing or even enhancing the expression level of the inhibitory FcgRIIB might be
a promising approach to predict or prevent IgG-mediated allergic reactions and also IgG-
FcgRIIB–controlled-IgE-mediated allergic reactions. The intravenous immunoglobulin (IVIg),
pooled human (hu) serum IgG from healthy donors, has been successfully used in high
concentrations (1-2 g/kg) to treat patients with acute flares of inflammatory autoimmune
diseases. Importantly, findings in animal autoimmune models have indicated that the …
a promising approach to predict or prevent IgG-mediated allergic reactions and also IgG-
FcgRIIB–controlled-IgE-mediated allergic reactions. The intravenous immunoglobulin (IVIg),
pooled human (hu) serum IgG from healthy donors, has been successfully used in high
concentrations (1-2 g/kg) to treat patients with acute flares of inflammatory autoimmune
diseases. Importantly, findings in animal autoimmune models have indicated that the …