Transcript analysis identifies differential uterine gene expression profile beyond the normal implantation window in mice

Q Xin, M Li, H Wang, S Cui, G Xia, S Kong - Theriogenology, 2017 - Elsevier
Uterine receptivity is defined as a state when the uterine milieu is favorable for blastocyst
implantation and it can only last for a limited time period. In this study, by utilizing the embryo
transfer model, it was observed that a portion of blastocysts could initiate implantation even
when transferred beyond the timing of normal uterine receptivity, while their mid-gestational
embryo development exhibited severe retardation, suggesting that the uterine status beyond
the normal implantation window is unconducive for normal implantation. We further …