Long noncoding RNA lncHand2 promotes liver repopulation via c-Met signaling
Y Wang, P Zhu, J Wang, X Zhu, J Luo, S Meng, J Wu… - Journal of …, 2018 - Elsevier
Background & Aims Long noncoding RNAs (lncRNAs) play important roles in various
biological processes, regulating gene expression by diverse mechanisms. However, how
lncRNAs regulate liver repopulation is unknown. Herein, we aimed to identify lncRNAs that
regulate liver repopulation and elucidate the signaling pathways involved. Methods Herein,
we performed 70% partial hepatectomy in wild-type and gene knockout mice. We then
performed transcriptomic analyses to identify a divergent lncRNA termed lncHand2 that is …
biological processes, regulating gene expression by diverse mechanisms. However, how
lncRNAs regulate liver repopulation is unknown. Herein, we aimed to identify lncRNAs that
regulate liver repopulation and elucidate the signaling pathways involved. Methods Herein,
we performed 70% partial hepatectomy in wild-type and gene knockout mice. We then
performed transcriptomic analyses to identify a divergent lncRNA termed lncHand2 that is …