Treatment of endometriosis

DL Olive, EA Pritts - New England Journal of Medicine, 2001 - Mass Medical Soc
DL Olive, EA Pritts
New England Journal of Medicine, 2001Mass Medical Soc
Endometriosis is the growth of endometrium outside the uterine cavity or myometrium
(endometriotic implants), usually in the peritoneal cavity (Figure 1). The question of how the
tissue attains this abnormal placement is controversial, although the predominant theory is
that retrograde menstruation is the cause. 1 Additional factors that may be important in
pathogenesis include immunologic abnormalities, endometrial disorders, and peritoneal
dysfunction. 1 The principal manifestations of endometriosis are pelvic pain and infertility. 2 …
Endometriosis is the growth of endometrium outside the uterine cavity or myometrium (endometriotic implants), usually in the peritoneal cavity (Figure 1). The question of how the tissue attains this abnormal placement is controversial, although the predominant theory is that retrograde menstruation is the cause.1 Additional factors that may be important in pathogenesis include immunologic abnormalities, endometrial disorders, and peritoneal dysfunction.1
The principal manifestations of endometriosis are pelvic pain and infertility.2 The extent of the pain is influenced primarily by the location and depth of the endometriotic implant, with deep implants in highly innervated areas most consistently associated with pain. Infertility . . .
The New England Journal Of Medicine